Basic Molecular Information

Basic Information

DICL ID
DICL_CP_0326400
PubChem CID
Molecular Formula
C13H21N5O3
Molecular Weight
295.343 g/mol
Synonyms/Alias
[BDBM86752]
InChI Key
BLZIYDWBKOOBIK-GYIHNLGQSA-N
InChI
InChI=1S/C13H21N5O3/c19-13(20)11-4-10-3-8(1-2-9(10)5-14-11)6-21-7-12-15-17-18-16-12/h8-11,14H,1-7H2,...
IUPAC Name
(3S,4aR,8aR)-6-(2H-tetrazol-5-ylmethoxymethyl)-1,2,3,4,4a,5,6,7,8,8a-decahydroisoquinoline-3-carboxylic acid
CAS Number
160126-61-4

Structure Information

Chemical Structure Visualization

SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF

21 23 0 0 0 0 0 0 0 0999 V2000
2.0854 -3.0529 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
0.5918 -3.1913 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
-0.2749 -1...

Experimental Data

Activity Data

Target Ion Channel
Glutamate receptor ionotropic subunit kainate 5
Uniprot Accession Number
Function
Inhibitor
Species
Rattus norvegicus (Rat)
IC50
N/A (Not available)
EC50
N/A (Not available)
Ki
Ki: 3060 nM
Kd
N/A (Not available)
Inhibition
N/A (Not available)

Experimental Conditions

pH
pH 7.5
Holding Potential
−70 mV mV
Temperature
37 °C
Test Method
Patch-clamping
Test Species
Not specified

Binding Information

Binding Site
Not specified
Binding Site Residue
Not specified

Disease Information

Related Disease
Not specified

References

URL
N/A (Not available)
PMID
Patent
N/A (Not available)

Computed Properties

Heavy Atom Count
21
Rotatable Bonds
5
logP
0.1953
Complexity
72.1982
TPSA (Ų)
113.02
H-Bond Donors
3
H-Bond Acceptors
6
Ring Count
3
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